Imidazole ketone erastin(Ferroptosis inducer IKE
Imidazole ketone erastin
CAS: 1801530-11-9
Molecular Formula: C35H35ClN6O5
Imidazole ketone erastin(Ferroptosis inducer IKE - Names and Identifiers
Imidazole ketone erastin(Ferroptosis inducer IKE - Physico-chemical Properties
| Molecular Formula | C35H35ClN6O5 |
| Molar Mass | 655.14 |
| Density | 1.34±0.1 g/cm3(Predicted) |
| Boling Point | 886.5±75.0 °C(Predicted) |
| Solubility | DMSO : 125 mg/mL (190.80 mM) |
| pKa | 6.12±0.10(Predicted) |
| Storage Condition | 2-8°C |
| In vivo study | In diffuse large B- cell lymphoma xenograft models, IKE inhibits system xc-, causes glutathione depletion, lipid peroxidation, and induces biomarkers of Iron death. |
Imidazole ketone erastin(Ferroptosis inducer IKE - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.526 ml | 7.632 ml | 15.264 ml |
| 5 mM | 0.305 ml | 1.526 ml | 3.053 ml |
| 10 mM | 0.153 ml | 0.763 ml | 1.526 ml |
| 5 mM | 0.031 ml | 0.153 ml | 0.305 ml |
Last Update：2024-01-02 23:10:35
Imidazole ketone erastin(Ferroptosis inducer IKE - Reference Information
| biological activity | Imidazole ketone erastin (PUN30119, IKE) is an effective, metabolically stable, selective system xc-inhibitors as well as ferroptosis inducers. |
| Target | Value |
Last Update：2024-04-09 02:00:14
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Product Name: IKE Visit Supplier Webpage Request for quotationCAS: 1801530-11-9
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Imidazoleketoneerastin Visit Supplier Webpage Request for quotationCAS: 1801530-11-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Imidazole ketone erastin Visit Supplier Webpage Request for quotationCAS: 1801530-11-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Imidazole ketone erastin Visit Supplier Webpage Request for quotationCAS: 1801530-11-9
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View History
Imidazole ketone erastin(Ferroptosis inducer IKE
489436-01-3
5-甲基-4-氧-3,4-二氢-噻吩[2,3-D]嘧啶-6-甲酸
2-(3-氯苯基)环丙基胺盐酸盐
8-(Phenylmethyl)-8-azabicyclo[3.2.1]octan-3-one hydrochloride
tris(2,3-dibromopropyl) isocyanurate
1,4-Butanediyl, 1-amino-2-carboxy-2-formyl-4-hydroxy- (9CI)
Ruthenium, tetrakis[μ-(octanoato-κO:κO′)]di-, (Ru-Ru)
Morpholinium, 4-methyl-4-[1-(2-thienyl)cyclohexyl]-, iodide (1:1)
2-硝基-4-(三氟甲基)苯甲醚
489436-01-3
5-甲基-4-氧-3,4-二氢-噻吩[2,3-D]嘧啶-6-甲酸
2-(3-氯苯基)环丙基胺盐酸盐
8-(Phenylmethyl)-8-azabicyclo[3.2.1]octan-3-one hydrochloride
tris(2,3-dibromopropyl) isocyanurate
1,4-Butanediyl, 1-amino-2-carboxy-2-formyl-4-hydroxy- (9CI)
Ruthenium, tetrakis[μ-(octanoato-κO:κO′)]di-, (Ru-Ru)
Morpholinium, 4-methyl-4-[1-(2-thienyl)cyclohexyl]-, iodide (1:1)
2-硝基-4-(三氟甲基)苯甲醚